Detalhe da pesquisa
1.
Combinatorial targeting of G-protein-coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug-induced liver injury.
Hepatology
; 78(1): 26-44, 2023 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36107019
2.
Graft-host coupling changes can lead to engraftment arrhythmia: a computational study.
J Physiol
; 601(13): 2733-2749, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37014103
3.
The crosstalk between gut barrier impairment, mitochondrial dysfunction, and microbiota alterations in people living with HIV.
J Med Virol
; 95(1): e28402, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36515414
4.
Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling.
FASEB J
; 36(1): e22060, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34862975
5.
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists.
Molecules
; 28(6)2023 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36985811
6.
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy.
FASEB J
; 35(1): e21271, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33368684
7.
Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics.
J Chem Inf Model
; 62(1): 196-209, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34914393
8.
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity.
J Immunol
; 204(9): 2535-2551, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32213564
9.
PCSK9 Induces Rat Smooth Muscle Cell Proliferation and Counteracts the Pleiotropic Effects of Simvastatin.
Int J Mol Sci
; 22(8)2021 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33923431
10.
Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis.
FASEB J
; 33(2): 2809-2822, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30303744
11.
The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis.
J Immunol
; 199(2): 718-733, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607110
12.
Differential effects of red yeast rice, Berberis aristata and Morus alba extracts on PCSK9 and LDL uptake.
Nutr Metab Cardiovasc Dis
; 29(11): 1245-1253, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31439394
13.
Learn from Your Elders: Developmental Biology Lessons to Guide Maturation of Stem Cell-Derived Cardiomyocytes.
Pediatr Cardiol
; 40(7): 1367-1387, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31388700
14.
Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties.
Molecules
; 24(6)2019 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30884797
15.
Disruption of TFGß-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand.
Pharmacol Res
; 131: 17-31, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29530598
16.
Geranylgeraniol prevents the simvastatin-induced PCSK9 expression: Role of the small G protein Rac1.
Pharmacol Res
; 122: 96-104, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28554582
17.
In vitro anticancer activity evaluation of new cationic platinum(II) complexes based on imidazole moiety.
Bioorg Med Chem
; 25(6): 1907-1913, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28254366
18.
Development of poly(lactide-co-glycolide) nanoparticles functionalized with a mitochondria penetrating peptide.
J Pept Sci
; 23(2): 182-188, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28093876
19.
Nanotraps with biomimetic surface as decoys for chemokines.
Nanomedicine
; 13(8): 2575-2585, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28756094
20.
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis.
Biochem Pharmacol
; 223: 116134, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38494064